FAM216B

Across TCGA patient cohorts, FAM216B protein abundance is significantly associated with the RNA expression of many other genes, with 196 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM216B-associated genes across cancer lineages are UQCC1, PIGU, and SLC7A6OS. Each is linked with FAM216B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM216B-to-partner and partner-to-FAM216B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM216B versus UQCC1 in LSCC, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM216B→partner) and Y-score (partner→FAM216B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UQCC1 →	-0.612	-1.364	.001	.002	3	1
LSCC	PIGU →	-0.849	-1.748	.003	.003	3	1
LSCC	SLC7A6OS →	-0.381	-1.716	<.001	.006	3	1
LSCC	USP10 →	-0.498	-1.963	.005	.002	3	1
LSCC	CAPS →	+1.524	+2.008	.009	.004	3	1
LSCC	BCCIP →	-0.442	-1.285	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 196 associations by consensus.

FAM216B vs UQCC1 — LSCC

Explore this scatter interactively →