FAM216B

Across TCGA patient cohorts, FAM216B mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FAM216B-associated genes across cancer lineages are MIR6515, LINC01737, and MIR6777. Each is linked with FAM216B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM216B-to-partner and partner-to-FAM216B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6515 grouped by FAM216B-low versus FAM216B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM216B→partner) and Y-score (partner→FAM216B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6515 →	+0.519	+4.335	<.001	.007	3	2
UCEC	LINC01737 →	+0.299	+4.335	<.001	.007	3	2
SKCM	MIR6777 →	+0.423	+4.199	<.001	.009	3	1
SKCM	HSPE1P22 →	+0.121	+3.490	.001	.008	3	1
SKCM	IGLVIVOR22-2 →	+0.241	+3.879	.001	.004	3	1
SKCM	MIR6752 →	+0.340	+4.199	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

MIR6515 by FAM216B expression — UCEC

Explore this box plot interactively →