Across TCGA patient cohorts, FAM216A RNA expression is significantly associated with the protein abundance of many other proteins, with 17,775 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM216A-associated proteins across cancer lineages are SQOR, EFTUD2, and SRSF9. Each is linked with FAM216A in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM216A-to-partner and partner-to-FAM216A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM216A→partner) and Y-score (partner→FAM216A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SQOR →	-0.552	-0.357	<.001	<.001	3	6
LSCC	EFTUD2 →	+0.181	+0.464	<.001	<.001	3	6
PDAC	SRSF9 →	+0.309	+0.263	.001	.002	3	5
OV	NELFCD →	+0.258	+0.525	.003	.001	3	5
LSCC	PARP1 →	+0.397	+0.369	<.001	.001	3	5
BRCA	RAB43 →	-0.380	-0.468	.003	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,775 associations by consensus.

Exploration

FAM216A survival (RNA) · tumor vs normal (RNA) · all FAM216A data types