Across TCGA patient cohorts, FAM216A mutation is significantly associated with the RNA expression of many other genes, with 875 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM216A-associated genes across cancer lineages are MIR98, RNU1-101P, and GCNT1P4. Each is linked with FAM216A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM216A-to-partner and partner-to-FAM216A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM216A→partner) and Y-score (partner→FAM216A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR98 →	+0.493	+4.192	<.001	.004	3	2
BLCA	RNU1-101P →	+0.197	+5.455	<.001	.001	3	1
BLCA	GCNT1P4 →	+0.178	+4.320	<.001	.002	3	1
BLCA	MIR548T →	+0.780	+6.038	<.001	<.001	3	1
BLCA	RN7SKP213 →	+0.154	+4.162	<.001	.003	3	1
BLCA	RN7SKP168 →	+0.193	+4.266	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 875 associations by consensus.

Exploration

FAM216A survival (RNA) · tumor vs normal (RNA) · all FAM216A data types