Across TCGA cell cohorts, FAM216A mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible FAM216A-associated genes across cancer lineages are GALNTL5, SERPINA7, and C1orf158. Each is linked with FAM216A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM216A-to-partner and partner-to-FAM216A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM216A→partner) and Y-score (partner→FAM216A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	GALNTL5 →	+0.033	+4.807	<.001	.006	3	1
BLOOD_Myeloma	SERPINA7 →	+0.459	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1orf158 →	+0.053	+4.807	<.001	.006	3	1
BLOOD_Myeloma	SLC22A12 →	+0.023	+4.807	<.001	.006	3	1
LARGE_INTESTINE	NCR3 →	+0.188	+3.854	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

FAM216A survival (RNA) · tumor vs normal (RNA) · all FAM216A data types