FAM215B

Across TCGA pan-cancer cohorts, FAM215B RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FAM215B data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FAM215B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM215B expression acts as an unfavorable survival marker, although some lineages such as PRAD and BRCA show a favorable association.

ACC, LIHC, and PRAD are the cancer types where FAM215B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	II,III,IV	0.324	0.697	.011	37	view →
LIHC	DFS	Median	All	0.476	0.592	.003	25	view →
PRAD	DFS	Median	All	0.882	0.675	.001	18	view →
KIRC	DFS	Tertile	All	0.739	0.817	.018	17	view →
BRCA	OS	Quartile	II,III,IV	0.978	0.941	.016	14	view →
KICH	OS	Median	All	0.700	0.957	.022	13	view →
THYM	OS	Median	All	1.000	0.922	.015	11	view →
COAD	OS	Tertile	All	0.782	0.899	.010	9	view →
LUSC	DFS	Quartile	All	0.813	0.668	.008	8	view →
UCS	DFS	Median	II,III,IV	0.206	0.478	.027	6	view →
OV	DFS	Median	III,IV	0.401	0.343	.034	6	view →
CHOL	DFS	Median	All	0.198	0.624	.016	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

FAM215B–ACC (DFS)

Open the ACC breakdown →