FAM215A

Across TCGA patient cohorts, FAM215A RNA expression is significantly associated with the go_rna of many other GO terms, with 7,077 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM215A-associated GO terms across cancer lineages are Antigen receptor-mediated signaling pathway, Regulation of CD4-positive, alpha-beta T cell activation, and Phosphatidylinositol biosynthetic process. Each is linked with FAM215A in more than 21 cancer types. Because this analysis shows association rather than direction, both FAM215A-to-partner and partner-to-FAM215A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen receptor-mediated signaling pathway grouped by FAM215A-low versus FAM215A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM215A→partner) and Y-score (partner→FAM215A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Antigen receptor-mediated signaling pathway →	+0.067	+0.200	<.001	<.001	3	22
STAD	Regulation of CD4-positive, alpha-beta T cell activation →	+0.055	+0.267	<.001	<.001	3	20
ESCA	Phosphatidylinositol biosynthetic process →	+0.052	+0.280	.002	.002	2	21
STAD	Regulation of cell morphogenesis →	+0.052	+0.247	<.001	<.001	3	20
STAD	Regulation of endocytosis →	+0.051	+0.239	<.001	<.001	3	20
STAD	Response to endoplasmic reticulum stress →	+0.059	+0.251	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,077 associations by consensus.

Antigen receptor-mediated signaling pathway by FAM215A expression — STAD

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