FAM214B

Across TCGA patient cohorts, FAM214B mutation is significantly associated with the RNA expression of many other genes, with 4,155 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM214B-associated genes across cancer lineages are RNU6-1338P, RNU6-1078P, and ZNF330. Each is linked with FAM214B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM214B-to-partner and partner-to-FAM214B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1338P grouped by FAM214B-low versus FAM214B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM214B→partner) and Y-score (partner→FAM214B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-1338P →	+0.382	+5.378	<.001	.006	3	3
HNSC	RNU6-1078P →	+0.278	+7.954	<.001	.008	3	2
COAD	ZNF330 →	+0.373	+3.199	.004	.009	3	2
UCEC	PSMD9 →	+0.483	+2.321	<.001	<.001	3	2
UCEC	LETM1 →	+0.558	+2.743	<.001	<.001	3	2
COAD	DAG1 →	+0.548	+3.250	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,155 associations by consensus.

RNU6-1338P by FAM214B expression — BRCA

Explore this box plot interactively →