FAM210B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM210B mutation is significantly associated with the RNA expression of many other genes, with 1,106 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM210B-associated genes across cancer lineages are DDX55P1, SUMO2P15, and RPL23AP90. Each is linked with FAM210B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM210B-to-partner and partner-to-FAM210B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DDX55P1 grouped by FAM210B-low versus FAM210B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM210B→partner) and Y-score (partner→FAM210B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECDDX55P1 →+0.150+2.720.001.00931
UCECSUMO2P15 →+0.321+2.423<.001.00431
UCECRPL23AP90 →+0.459+3.156<.001<.00131
UCECPOM121C →+0.588+3.638<.001.00131
UCECTMEM269 →+0.199+3.476.003.00331
UCECSYNRG →+0.591+3.617.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,106 associations by consensus.

DDX55P1 by FAM210B expression — UCEC

Box plot of DDX55P1 in FAM210B-low vs FAM210B-high samples in UCEC.

Explore this box plot interactively →

Exploration