FAM210B

Across TCGA patient cohorts, FAM210B mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM210B-associated genes across cancer lineages are eIF4E, ATM, and MEK1. Each is linked with FAM210B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM210B-to-partner and partner-to-FAM210B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by FAM210B-low versus FAM210B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM210B→partner) and Y-score (partner→FAM210B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.268	+3.169	.020	.020	3	1
UCEC	ATM →	-0.574	-3.169	.021	.020	3	1
UCEC	MEK1 →	+0.510	+3.169	.011	.020	1	1
UCEC	Collagen-VI →	-0.236	-3.169	.037	.020	1	1
UCEC	Cyclin-B1 →	+0.612	+3.169	.047	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

eIF4E by FAM210B expression — UCEC

Explore this box plot interactively →