FAM20B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM20B protein abundance is significantly associated with the RNA expression of many other genes, with 12,844 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM20B-associated genes across cancer lineages are TOMM20, C1orf56, and H3-3A. Each is linked with FAM20B in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM20B-to-partner and partner-to-FAM20B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM20B versus TOMM20 in LSCC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM20B→partner) and Y-score (partner→FAM20B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCTOMM20 →+0.704+0.498<.001<.00136
LSCCC1orf56 →+0.555+0.456<.001<.00135
HNSCH3-3A →+0.662+0.472<.001<.00135
LSCCLINC01703 →+0.795+0.391<.001<.00135
LSCCRASSF2 →-0.641-0.451<.001<.00134
HNSCPEX5L →+0.620+0.367.005<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,844 associations by consensus.

FAM20B vs TOMM20 — LSCC

Per-sample scatter of FAM20B vs TOMM20 in LSCC (Pearson r = 0.65).

Explore this scatter interactively →

Exploration