FAM20B

Across TCGA patient cohorts, FAM20B mutation is significantly associated with the RNA expression of many other genes, with 1,787 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM20B-associated genes across cancer lineages are RNU6-74P, MIR549A, and RN7SKP252. Each is linked with FAM20B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM20B-to-partner and partner-to-FAM20B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-74P grouped by FAM20B-low versus FAM20B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM20B→partner) and Y-score (partner→FAM20B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-74P →	+0.129	+2.484	.006	.002	3	3
CESC	MIR549A →	+0.266	+4.757	<.001	.004	3	2
LUAD	RN7SKP252 →	+0.272	+7.108	<.001	<.001	3	2
STAD	RBMY2GP →	+0.039	+5.105	.002	.008	3	2
UCEC	RFKP1 →	+0.079	+2.242	.001	.005	3	2
UCEC	EIF3JP1 →	+0.142	+2.018	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,787 associations by consensus.

RNU6-74P by FAM20B expression — UCEC

Explore this box plot interactively →