FAM20B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM20B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,585 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM20B-associated GO terms across cancer lineages are Mitotic cytokinesis, Heterochromatin formation, and Regulation of chromosome condensation. Each is linked with FAM20B in more than 13 cancer types. Because this analysis shows association rather than direction, both FAM20B-to-partner and partner-to-FAM20B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic cytokinesis grouped by FAM20B-low versus FAM20B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM20B→partner) and Y-score (partner→FAM20B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCMitotic cytokinesis →+0.073+0.897.003.003314
LARGE_INTESTINEHeterochromatin formation →+0.066+0.795<.001<.001314
BLOOD_LymphomaRegulation of chromosome condensation →+0.168+0.710<.001.003314
OVARYHeterochromatin organization →+0.066+0.673<.001.001314
LIVERNegative regulation of gene expression, epigenetic →+0.081+0.772<.001.001313
LIVERPositive regulation of mRNA processing →+0.103+0.671.003.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,585 associations by consensus.

Mitotic cytokinesis by FAM20B expression — LUNG_NSCLC_LUSC

Box plot of Mitotic cytokinesis in FAM20B-low vs FAM20B-high samples in LUNG_NSCLC_LUSC.

Explore this box plot interactively →

Exploration