FAM20B

Across TCGA cell cohorts, FAM20B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM20B-associated genes across cancer lineages are REG1B, C10orf53, and FAM218A. Each is linked with FAM20B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM20B-to-partner and partner-to-FAM20B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG1B grouped by FAM20B-low versus FAM20B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM20B→partner) and Y-score (partner→FAM20B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	REG1B →	+3.309	+3.518	<.001	.001	3	1
LARGE_INTESTINE	C10orf53 →	+0.013	+3.217	<.001	.006	3	1
LARGE_INTESTINE	FAM218A →	+0.372	+2.906	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

REG1B by FAM20B expression — LARGE_INTESTINE

Explore this box plot interactively →