FAM20A

Across TCGA patient cohorts, FAM20A mutation is significantly associated with the RNA expression of many other genes, with 1,975 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM20A-associated genes across cancer lineages are MIR551B, LINC00363, and RNU1-17P. Each is linked with FAM20A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM20A-to-partner and partner-to-FAM20A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR551B grouped by FAM20A-low versus FAM20A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM20A→partner) and Y-score (partner→FAM20A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR551B →	+0.276	+7.731	<.001	.009	3	2
BRCA	LINC00363 →	+0.142	+7.731	<.001	.009	3	2
UCEC	RNU1-17P →	+0.188	+2.272	<.001	.002	3	2
BLCA	TUBBP11 →	+0.194	+5.106	.001	.008	3	2
UCEC	TDGF1P1 →	+0.059	+2.420	.001	.003	3	2
UCEC	LINC01072 →	+0.105	+2.126	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,975 associations by consensus.

MIR551B by FAM20A expression — BRCA

Explore this box plot interactively →