FAM20A

Across TCGA cell cohorts, FAM20A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,672 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FAM20A-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Cytoplasmic translation. Each is linked with FAM20A in more than 10 cancer types. Because this analysis shows association rather than direction, both FAM20A-to-partner and partner-to-FAM20A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by FAM20A-low versus FAM20A-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM20A→partner) and Y-score (partner→FAM20A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of myoblast fusion →	+0.110	+0.295	<.001	.001	2	11
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.092	+0.184	<.001	<.001	3	10
BREAST	Cytoplasmic translation →	+0.078	+0.463	<.001	.002	3	10
LARGE_INTESTINE	Negative regulation of gene expression, epigenetic →	+0.056	+0.314	<.001	<.001	3	9
BREAST	Positive regulation of double-strand break repair →	+0.089	+0.728	<.001	<.001	3	8
BREAST	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.140	+0.438	.001	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,672 associations by consensus.

Regulation of myoblast fusion by FAM20A expression — PANCREAS

Explore this box plot interactively →