FAM207A

Across TCGA patient cohorts, FAM207A mutation is significantly associated with the RNA expression of many other genes, with 695 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM207A-associated genes across cancer lineages are RN7SKP181, TDGF1P1, and IGKV1OR2-118. Each is linked with FAM207A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM207A-to-partner and partner-to-FAM207A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP181 grouped by FAM207A-low versus FAM207A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM207A→partner) and Y-score (partner→FAM207A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP181 →	+0.118	+2.648	<.001	.002	3	2
UCEC	TDGF1P1 →	+0.068	+2.513	.001	.007	3	2
UCEC	IGKV1OR2-118 →	+0.169	+2.036	.008	.003	3	1
UCEC	CCL5 →	+1.072	+2.436	.003	.002	3	1
UCEC	MIR6859-2 →	+0.361	+1.990	<.001	.009	3	1
UCEC	NOL12 →	+0.365	+1.939	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 695 associations by consensus.

RN7SKP181 by FAM207A expression — UCEC

Explore this box plot interactively →