Across TCGA patient cohorts, FAM205A mutation is significantly associated with the RNA expression of many other genes, with 3,504 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM205A-associated genes across cancer lineages are TIMM8B, SLC25A4, and MRPL17. Each is linked with FAM205A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM205A-to-partner and partner-to-FAM205A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM205A→partner) and Y-score (partner→FAM205A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIMM8B →	+0.370	+3.743	.002	<.001	3	2
UCEC	SLC25A4 →	+0.508	+1.949	<.001	.001	3	2
UCEC	MRPL17 →	+0.264	+1.673	.009	.003	3	2
UCEC	SLC13A3 →	-0.490	-2.071	.003	.005	3	2
UCEC	SENP3 →	+0.469	+2.446	<.001	.001	3	2
UCEC	CLPB →	+0.377	+2.535	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,504 associations by consensus.

Exploration

FAM205A survival (RNA) · tumor vs normal (RNA) · all FAM205A data types