Across TCGA cell cohorts, FAM205A mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM205A-associated genes across cancer lineages are GPR101, TAS2R39, and GUCY2D. Each is linked with FAM205A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM205A-to-partner and partner-to-FAM205A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM205A→partner) and Y-score (partner→FAM205A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GPR101 →	+0.070	+4.906	<.001	.006	3	1
OESOPHAGUS	TAS2R39 →	+0.043	+4.906	<.001	.006	3	1
URINARY_TRACT	GUCY2D →	+0.382	+3.643	<.001	.007	3	1
URINARY_TRACT	SLC22A7 →	+0.102	+3.584	.008	.005	3	1
URINARY_TRACT	SCML4 →	+0.414	+3.807	.009	.005	3	1
LUNG_SCLC	PRG3 →	+0.020	+4.058	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

FAM205A survival (RNA) · tumor vs normal (RNA) · all FAM205A data types