FAM204A

Across TCGA pan-cancer cohorts, FAM204A mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FAM204A data layer compared with 20 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher FAM204A mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FAM204A expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC and LUAD are the cancer types where FAM204A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	II,III,IV	1.000	0.587	.010	20	view →
LUAD	DFS	Quartile	All	0.879	1.000	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

FAM204A–LSCC (OS)

Open the LSCC breakdown →