FAM204A

Across TCGA patient cohorts, FAM204A protein abundance is significantly associated with the protein abundance of many other proteins, with 9,892 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM204A-associated proteins across cancer lineages are SMC3, RBM25, and BRD8. Each is linked with FAM204A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM204A-to-partner and partner-to-FAM204A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM204A versus SMC3 in LSCC, with a Pearson correlation of 0.61.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM204A→partner) and Y-score (partner→FAM204A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMC3 →	+0.415	+0.469	<.001	<.001	3	4
LSCC	RBM25 →	+0.300	+0.378	<.001	<.001	3	4
LSCC	BRD8 →	+0.380	+0.523	<.001	<.001	3	4
OV	BRMS1_S237 →	+1.356	+1.076	.001	<.001	3	4
LSCC	CBLL1 →	+0.217	+0.275	<.001	.001	3	4
OV	WBP4_S262 →	+1.411	+0.941	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,892 associations by consensus.

FAM204A vs SMC3 — LSCC

Explore this scatter interactively →