FAM204A

Across TCGA patient cohorts, FAM204A mutation is significantly associated with the RNA expression of many other genes, with 317 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM204A-associated genes across cancer lineages are PAXIP1-DT, NOL12, and INO80B-WBP1. Each is linked with FAM204A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM204A-to-partner and partner-to-FAM204A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PAXIP1-DT grouped by FAM204A-low versus FAM204A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM204A→partner) and Y-score (partner→FAM204A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PAXIP1-DT →	+0.664	+3.346	<.001	.005	3	1
UCEC	NOL12 →	+0.438	+3.202	.002	.009	3	1
UCEC	INO80B-WBP1 →	+0.163	+3.477	<.001	.006	3	1
UCEC	TBC1D3L →	+0.542	+2.719	.001	.002	3	1
UCEC	F8A2 →	+0.025	+3.109	.003	.007	3	1
UCEC	CCL3 →	+1.220	+3.491	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 317 associations by consensus.

PAXIP1-DT by FAM204A expression — UCEC

Explore this box plot interactively →