FAM200B

Across TCGA patient cohorts, FAM200B mutation is significantly associated with the RNA expression of many other genes, with 2,228 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM200B-associated genes across cancer lineages are TRGJP2, BPY2DP, and RN7SKP245. Each is linked with FAM200B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM200B-to-partner and partner-to-FAM200B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRGJP2 grouped by FAM200B-low versus FAM200B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM200B→partner) and Y-score (partner→FAM200B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRGJP2 →	+0.829	+3.489	<.001	.005	3	2
COAD	BPY2DP →	+0.238	+5.409	<.001	.001	3	2
CESC	RN7SKP245 →	+0.096	+4.812	<.001	.006	3	2
UCEC	SMIM15P2 →	+0.432	+1.891	.004	.003	3	2
BRCA	RNU4ATAC7P →	+0.278	+8.055	<.001	.007	3	1
BRCA	LINC02423 →	+0.078	+7.731	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,228 associations by consensus.

TRGJP2 by FAM200B expression — COAD

Explore this box plot interactively →