FAM200B

Across TCGA patient cohorts, FAM200B mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM200B-associated genes across cancer lineages are 14-3-3_beta, A-Raf_pS299, and ERK2. Each is linked with FAM200B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM200B-to-partner and partner-to-FAM200B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by FAM200B-low versus FAM200B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM200B→partner) and Y-score (partner→FAM200B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.100	-2.432	.007	.018	3	1
UCEC	A-Raf_pS299 →	-0.147	-2.807	.001	.003	3	1
UCEC	ERK2 →	+0.216	+2.169	.002	.003	3	1
UCEC	INPP4B →	-0.255	-3.584	.035	.002	3	1
UCEC	JNK_pT183_Y185 →	-0.125	-1.752	.047	.014	3	1
UCEC	Ku80 →	+0.229	+1.778	.009	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

14-3-3_beta by FAM200B expression — UCEC

Explore this box plot interactively →