FAM200B

Across TCGA cell cohorts, FAM200B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,336 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM200B-associated GO terms across cancer lineages are Regulation of tRNA catabolic process, Negative regulation of tRNA catabolic process, and Regulation of tRNA stability. Each is linked with FAM200B in more than 10 cancer types. Because this analysis shows association rather than direction, both FAM200B-to-partner and partner-to-FAM200B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tRNA catabolic process grouped by FAM200B-low versus FAM200B-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM200B→partner) and Y-score (partner→FAM200B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of tRNA catabolic process →	-0.199	-0.873	.001	.005	2	11
BLOOD_Myeloma	Negative regulation of tRNA catabolic process →	-0.199	-0.873	.001	.005	2	11
BLOOD_Myeloma	Regulation of tRNA stability →	-0.199	-0.873	.001	.005	2	11
BLOOD_Myeloma	tRNA stabilization →	-0.199	-0.873	.001	.005	2	11
PANCREAS	Glucosamine metabolic process →	+0.146	+1.149	<.001	<.001	3	10
SOFT_TISSUE	DAMP biosynthetic process →	+0.147	+0.959	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,336 associations by consensus.

Regulation of tRNA catabolic process by FAM200B expression — BLOOD_Myeloma

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