FAM200B

Across TCGA cell cohorts, FAM200B mutation is significantly associated with the RNA expression of many other genes, with 256 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM200B-associated genes across cancer lineages are GNG8, PRAMEF14, and CXorf51B. Each is linked with FAM200B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM200B-to-partner and partner-to-FAM200B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GNG8 grouped by FAM200B-low versus FAM200B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM200B→partner) and Y-score (partner→FAM200B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GNG8 →	+0.268	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	PRAMEF14 →	+0.012	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	CXorf51B →	+2.602	+5.228	<.001	.005	3	1
BREAST	KRTAP10-1 →	+0.019	+5.169	<.001	.005	3	1
BLOOD_Lymphoma	KRTAP3-2 →	+0.083	+6.247	<.001	<.001	3	1
LARGE_INTESTINE	SLC25A1 →	+0.663	+2.502	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 256 associations by consensus.

GNG8 by FAM200B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →