Across TCGA pan-cancer cohorts, FAM200A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FAM200A data layer compared with 25 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher FAM200A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM200A expression acts as an unfavorable survival marker.

SKCM, GBM, and UCEC are the cancer types where FAM200A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	II,III,IV	0.232	0.735	.011	15	view →
GBM	DFS	Median	All	0.043	0.243	.003	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: FAM200A tumor-vs-normal RNA expression · all FAM200A data types