Across TCGA pan-cancer cohorts, FAM197Y7 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of FAM197Y7’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where FAM197Y7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM197Y7 is over-expressed in tumor.
LIHC are the cancer types where FAM197Y7 tumor–normal differential expression is most reproducible.