FAM197Y10

Across TCGA pan-cancer cohorts, FAM197Y10 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated FAM197Y10 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FAM197Y10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM197Y10 expression acts as an unfavorable survival marker.

HNSC, COAD, and LIHC are the cancer types where FAM197Y10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.082	0.751	<.001	144	view →
COAD	OS	Tertile	All	0.039	0.871	<.001	144	view →
LIHC	OS	Tertile	All	0.092	0.783	<.001	99	view →
STAD	OS	Tertile	IV	0.156	0.506	.021	18	view →
KIRC	DFS	Tertile	All	0.188	0.796	.003	18	view →
UCEC	OS	Tertile	All	0.599	0.873	.039	18	view →
SARC	DFS	Tertile	All	0.130	0.632	.045	9	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FAM197Y10–HNSC (OS)

Open the HNSC breakdown →