FAM192BP

Across TCGA pan-cancer cohorts, FAM192BP RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of FAM192BP’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where FAM192BP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FAM192BP is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, BLCA, and HNSC are the cancer types where FAM192BP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM192BP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	+0.530	<.001	10	view →
BLCA	All	III,IV	+0.245	.001	9	view →
HNSC	Male	II,III,IV	+0.147	<.001	8	view →
LUAD	All	IV	+0.164	.008	6	view →
CHOL	All	All	+0.355	<.001	5	view →
LUSC	Male	II,III,IV	+0.263	<.001	5	view →
STAD	Male	All	+0.248	.010	4	view →
THCA	All	All	−0.116	.012	4	view →
LIHC	All	II,III,IV	+0.075	.014	4	view →
BRCA	All	All	+0.075	.032	3	view →
KIRP	Male	II,III,IV	+0.155	.026	2	view →
KICH	Female	III,IV	+0.123	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

FAM192BP–COAD

Open the COAD breakdown →