FAM189B

Across TCGA patient cohorts, FAM189B RNA expression is significantly associated with the protein abundance of many other proteins, with 17,737 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM189B-associated proteins across cancer lineages are USP39, PARP1, and PRCC. Each is linked with FAM189B in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM189B-to-partner and partner-to-FAM189B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM189B versus USP39 in LSCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM189B→partner) and Y-score (partner→FAM189B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	USP39 →	+0.364	+0.791	<.001	<.001	3	6
HNSC	PARP1 →	+0.564	+0.744	<.001	<.001	3	6
LSCC	PRCC →	+0.321	+0.589	<.001	<.001	3	6
LSCC	PRPF4 →	+0.337	+0.810	<.001	<.001	3	6
HNSC	POLR1F →	+0.398	+0.630	<.001	.001	3	6
BRCA	ZFR →	+0.221	+0.674	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,737 associations by consensus.

FAM189B vs USP39 — LSCC

Explore this scatter interactively →