FAM189A2

Across TCGA patient cohorts, FAM189A2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,180 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM189A2-associated proteins across cancer lineages are FAM189A2_S275, SPTBN1, and PES1. Each is linked with FAM189A2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM189A2-to-partner and partner-to-FAM189A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM189A2 versus FAM189A2_S275 in UCEC, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM189A2→partner) and Y-score (partner→FAM189A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM189A2_S275 →	+1.144	+1.826	<.001	<.001	3	6
GBM	SPTBN1 →	+0.569	+1.345	<.001	<.001	3	6
BRCA	PES1 →	-0.352	-0.852	<.001	<.001	3	6
HNSC	PPP1R12B →	+0.667	+0.515	<.001	<.001	3	6
CCRCC	SLC9A3R2 →	+0.442	+0.520	<.001	<.001	3	5
HNSC	TBRG4 →	-0.405	-0.816	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,180 associations by consensus.

FAM189A2 vs FAM189A2_S275 — UCEC

Explore this scatter interactively →