FAM189A2

Across TCGA patient cohorts, FAM189A2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,142 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM189A2-associated genes across cancer lineages are PRODH, RASL10A, and SALL4. Each is linked with FAM189A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM189A2-to-partner and partner-to-FAM189A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM189A2 versus PRODH in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM189A2→partner) and Y-score (partner→FAM189A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+1.069	+0.639	<.001	<.001	3	1
GBM	RASL10A →	+1.084	+0.709	.008	.005	3	1
GBM	SALL4 →	-0.880	-0.955	<.001	.002	3	1
GBM	GLA →	-0.371	-0.527	.001	.003	3	1
GBM	CD9 →	+0.594	+0.849	.006	.006	3	1
GBM	ZNF423 →	+0.879	+0.592	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,142 associations by consensus.

FAM189A2 vs PRODH — GBM

Explore this scatter interactively →