FAM189A2

Across TCGA cell cohorts, FAM189A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,413 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FAM189A2-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Vacuolar transport. Each is linked with FAM189A2 in more than 8 cancer types. Because this analysis shows association rather than direction, both FAM189A2-to-partner and partner-to-FAM189A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by FAM189A2-low versus FAM189A2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM189A2→partner) and Y-score (partner→FAM189A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.124	+0.796	.004	.001	3	9
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.165	+0.993	.003	.001	3	9
LUNG_SCLC	Vacuolar transport →	+0.046	+1.279	.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Respiratory electron transport chain →	+0.104	+0.932	<.001	.007	3	8
OESOPHAGUS	Regulation of translational initiation →	+0.093	+0.876	.006	.001	3	8
OESOPHAGUS	Aerobic respiration →	+0.139	+1.307	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,413 associations by consensus.

Negative regulation of myoblast fusion by FAM189A2 expression — OESOPHAGUS

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