FAM189A1

Across TCGA patient cohorts, FAM189A1 protein abundance is significantly associated with the RNA expression of many other genes, with 321 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM189A1-associated genes across cancer lineages are PLAT, TFPI2, and ACTR3C. Each is linked with FAM189A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM189A1-to-partner and partner-to-FAM189A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM189A1 versus PLAT in GBM, with a Pearson correlation of -0.93.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM189A1→partner) and Y-score (partner→FAM189A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLAT →	-1.323	-1.466	.006	.001	3	1
GBM	TFPI2 →	+1.113	+1.098	.001	.002	3	1
GBM	ACTR3C →	+1.001	+1.098	.001	.002	3	1
GBM	NUP88 →	-0.663	-1.466	.004	.001	3	1
GBM	SLC6A4 →	-0.373	-0.949	.002	.007	3	1
GBM	ASIC2 →	+1.177	+1.098	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 321 associations by consensus.

FAM189A1 vs PLAT — GBM

Explore this scatter interactively →