FAM187B2P

Across TCGA pan-cancer cohorts, FAM187B2P RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of FAM187B2P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where FAM187B2P RNA is repressed in tumor relative to normal tissue. In most cancer types FAM187B2P is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, COAD, and LUSC are the cancer types where FAM187B2P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM187B2P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	II,III,IV	−0.593	<.001	11	view →
COAD	Female	II,III,IV	−0.646	<.001	10	view →
LUSC	Female	All	−0.718	<.001	7	view →
UCEC	All	III,IV	−0.864	<.001	6	view →
BRCA	All	III,IV	−0.557	<.001	6	view →
LUAD	Female	II,III,IV	−0.528	<.001	6	view →
READ	All	All	−0.387	<.001	5	view →
KIRP	All	III,IV	−0.178	.013	3	view →
CHOL	All	II,III,IV	−0.480	.030	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

FAM187B2P–KICH

Open the KICH breakdown →