Across TCGA patient cohorts, FAM187A mutation is significantly associated with the RNA expression of many other genes, with 246 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM187A-associated genes across cancer lineages are MIR98, RAB11A, and UBXN8. Each is linked with FAM187A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM187A-to-partner and partner-to-FAM187A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM187A→partner) and Y-score (partner→FAM187A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR98 →	+0.320	+2.801	<.001	.005	3	1
UCEC	RAB11A →	+0.610	+3.243	.001	.008	3	1
UCEC	UBXN8 →	+0.607	+3.330	.009	.005	3	1
UCEC	ERICH1 →	+0.463	+3.459	.002	.005	3	1
UCEC	TLE6 →	+0.907	+3.480	.003	.002	3	1
UCEC	STAG3L4 →	+0.644	+3.191	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 246 associations by consensus.

Exploration

FAM187A survival (RNA) · tumor vs normal (RNA) · all FAM187A data types