FAM187A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM187A mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM187A-associated genes across cancer lineages are CD8+ naive T-cells, Endothelial cells, and lymphatic Endothelial cells. Each is linked with FAM187A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM187A-to-partner and partner-to-FAM187A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM187A→partner) and Y-score (partner→FAM187A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCD8+ naive T-cells →+0.027+2.364.042.01931
UCECEndothelial cells →-0.039-2.279.042.03631
UCEClymphatic Endothelial cells →-0.024-2.268.040.03631
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration