Across TCGA pan-cancer cohorts, FAM185BP RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated FAM185BP data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher FAM185BP RNA is associated with better overall survival. In most high-consensus cancer types, elevated FAM185BP expression acts as an unfavorable survival marker, although some lineages such as CHOL and HNSC show a favorable association.

CHOL, HNSC, and LGG are the cancer types where FAM185BP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Median	All	0.888	0.176	.002	34	view →
HNSC	OS	Median	All	0.825	0.708	.002	30	view →
LGG	OS	Tertile	All	0.748	0.875	.002	28	view →
UVM	OS	Quartile	All	0.910	0.405	.010	27	view →
SKCM	DFS	Median	All	0.245	0.156	<.001	25	view →
READ	OS	Tertile	II,III,IV	1.000	0.287	<.001	22	view →
ACC	DFS	Tertile	All	0.477	0.784	.003	22	view →
KIRC	DFS	Tertile	II,III,IV	0.809	0.572	.008	20	view →
LUSC	OS	Tertile	All	0.840	0.721	.006	18	view →
PRAD	DFS	Median	All	0.907	0.959	.004	16	view →
DLBC	DFS	Median	II,III,IV	1.000	0.535	.015	13	view →
KICH	OS	Tertile	All	0.589	0.938	.016	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

Exploration

Same gene, other analysis: FAM185BP tumor-vs-normal RNA expression · all FAM185BP data types