Across TCGA patient cohorts, FAM185A mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM185A-associated genes across cancer lineages are MIR6853, RNA5SP143, and MIR548AD. Each is linked with FAM185A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM185A-to-partner and partner-to-FAM185A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM185A→partner) and Y-score (partner→FAM185A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6853 →	+0.364	+9.057	<.001	.003	3	1
BRCA	RNA5SP143 →	+0.345	+7.731	<.001	.009	3	1
BRCA	MIR548AD →	+0.338	+8.471	<.001	.005	3	1
BRCA	TSPY19P →	+0.094	+8.055	<.001	.007	3	1
BRCA	RNU6-261P →	+0.379	+9.057	<.001	.003	3	1
BRCA	RNU7-164P →	+0.547	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

Exploration

FAM185A survival (RNA) · tumor vs normal (RNA) · all FAM185A data types