Across TCGA cell cohorts, FAM185A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM185A-associated genes across cancer lineages are OR13D1, CELA2B, and OR8B4. Each is linked with FAM185A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM185A-to-partner and partner-to-FAM185A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM185A→partner) and Y-score (partner→FAM185A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR13D1 →	+0.039	+4.467	<.001	.004	3	1
LARGE_INTESTINE	CELA2B →	+0.062	+4.273	<.001	.006	3	1
CNS	OR8B4 →	+0.060	+6.357	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

FAM185A survival (RNA) · tumor vs normal (RNA) · all FAM185A data types