FAM184B

Across TCGA pan-cancer cohorts, FAM184B mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of FAM184B’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where FAM184B mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types FAM184B is over-expressed in tumor.

HNSC and LSCC are the cancer types where FAM184B tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM184B mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.763	.002	8	view →
LSCC	Male	III,IV	+0.864	<.001	7	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

FAM184B–HNSC

Open the HNSC breakdown →