FAM184A

Across TCGA patient cohorts, FAM184A mutation is significantly associated with the RNA expression of many other genes, with 4,475 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM184A-associated genes across cancer lineages are RAD51, TSEN54, and PKN3. Each is linked with FAM184A in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM184A-to-partner and partner-to-FAM184A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by FAM184A-low versus FAM184A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM184A→partner) and Y-score (partner→FAM184A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD51 →	+0.909	+2.964	<.001	<.001	3	5
SKCM	TSEN54 →	+0.289	+2.019	.005	<.001	3	4
UCEC	PKN3 →	+0.818	+2.283	<.001	<.001	3	4
UCEC	OIP5 →	+0.940	+2.606	<.001	<.001	3	4
UCEC	FANCE →	+0.508	+4.021	<.001	<.001	3	4
UCEC	WRAP73 →	+0.353	+1.787	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,475 associations by consensus.

RAD51 by FAM184A expression — UCEC

Explore this box plot interactively →