FAM184A

Across TCGA patient cohorts, FAM184A mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM184A-associated genes across cancer lineages are PR, Rab25, and Caspase-8. Each is linked with FAM184A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM184A-to-partner and partner-to-FAM184A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PR grouped by FAM184A-low versus FAM184A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM184A→partner) and Y-score (partner→FAM184A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PR →	-0.168	-2.222	.036	.010	3	3
UCEC	Rab25 →	-0.325	-2.115	.002	.016	3	2
UCEC	Caspase-8 →	-0.239	-3.221	.002	<.001	3	2
SKCM	Caveolin-1 →	-0.527	-2.321	.026	.032	3	2
UCEC	Ku80 →	+0.222	+1.536	.003	.005	3	2
UCEC	MEK1 →	+0.495	+2.058	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

PR by FAM184A expression — UCEC

Explore this box plot interactively →