FAM184A

Across TCGA cell cohorts, FAM184A mutation is significantly associated with the mutation status of many other genes, with 5,153 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM184A-associated genes across cancer lineages are BCL11B, ALMS1, and ZFP64. Each is linked with FAM184A in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM184A-to-partner and partner-to-FAM184A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCL11B grouped by FAM184A-low versus FAM184A-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM184A→partner) and Y-score (partner→FAM184A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	BCL11B →	+4.857	+4.297	.009	.009	1	5
BLOOD_Lymphoma	ALMS1 →	+2.925	+4.618	.001	.001	1	5
BLOOD_Leukemia	ZFP64 →	+3.038	+3.347	.002	.002	1	5
LARGE_INTESTINE	C8A →	+2.678	+2.807	.006	.006	1	5
CNS	SETD2 →	+3.055	+3.786	.006	.006	1	4
BLOOD_Lymphoma	COL5A1 →	+2.832	+3.601	.008	.008	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,153 associations by consensus.

BCL11B by FAM184A expression — BREAST

Explore this box plot interactively →