Across TCGA patient cohorts, FAM183A mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM183A-associated genes across cancer lineages are MIR5093, ATP2B2-IT1, and OR5D2P. Each is linked with FAM183A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM183A-to-partner and partner-to-FAM183A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM183A→partner) and Y-score (partner→FAM183A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR5093 →	+0.733	+3.474	<.001	.006	3	2
OV	ATP2B2-IT1 →	+0.075	+4.991	.001	.009	3	2
UCEC	OR5D2P →	+0.069	+4.260	.007	.007	3	2
OV	RNU6-660P →	+0.390	+4.991	<.001	.009	3	2
COAD	SNORA41B →	+0.296	+4.537	<.001	.006	3	1
COAD	MTND5P6 →	+0.152	+4.484	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

FAM183A survival (RNA) · tumor vs normal (RNA) · all FAM183A data types