Across TCGA pan-cancer cohorts, FAM182A Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FAM182A data layer compared with 17 for mass-spec protein and 4 for mass-spec protein.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher FAM182A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM182A expression acts as an unfavorable survival marker.
LIHC are the cancer types where FAM182A Mutation most reproducibly stratifies survival.