FAM181A-AS1

Across TCGA pan-cancer cohorts, FAM181A-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated FAM181A-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FAM181A-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated FAM181A-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BRCA show a favorable association.

UCEC, LGG, and BRCA are the cancer types where FAM181A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	IV	0.864	0.453	.009	56	view →
LGG	OS	Median	All	0.733	0.888	<.001	52	view →
BRCA	DFS	Tertile	All	0.623	0.476	.005	32	view →
LUAD	OS	Median	II,III,IV	0.774	0.639	.001	24	view →
READ	DFS	Tertile	III,IV	0.268	0.635	.019	21	view →
SARC	OS	Tertile	All	0.601	0.342	.001	17	view →
KIRC	DFS	Tertile	All	0.710	0.815	.006	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
BLCA	OS	Tertile	All	0.678	0.574	.035	4	view →
PRAD	DFS	Median	All	0.961	0.918	.026	4	view →
LIHC	OS	Tertile	II,III,IV	0.543	0.733	.048	3	view →
PCPG	OS	Median	All	1.000	0.740	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

FAM181A-AS1–UCEC (DFS)

Open the UCEC breakdown →