Across TCGA patient cohorts, FAM180B protein abundance is significantly associated with the RNA expression of many other genes, with 2,665 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM180B-associated genes across cancer lineages are LMOD2, CHRDL1, and SRPX. Each is linked with FAM180B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM180B-to-partner and partner-to-FAM180B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM180B→partner) and Y-score (partner→FAM180B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LMOD2 →	+2.150	+0.611	<.001	<.001	3	2
BRCA	CHRDL1 →	+1.976	+0.859	.001	<.001	3	2
BRCA	SRPX →	+1.664	+0.900	<.001	<.001	3	2
BRCA	MEDAG →	+2.744	+1.436	<.001	<.001	3	2
BRCA	MEOX2 →	+1.669	+0.905	<.001	<.001	3	2
HNSC	PRUNE2 →	+1.369	+0.429	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,665 associations by consensus.

Exploration

FAM180B survival (RNA) · tumor vs normal (RNA) · all FAM180B data types