Across TCGA patient cohorts, FAM180B mutation is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM180B-associated genes across cancer lineages are MIR3915, MIR4529, and RN7SL217P. Each is linked with FAM180B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM180B-to-partner and partner-to-FAM180B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM180B→partner) and Y-score (partner→FAM180B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3915 →	+0.281	+4.736	<.001	.003	3	1
UCEC	MIR4529 →	+0.275	+4.049	<.001	.008	3	1
UCEC	RN7SL217P →	+0.123	+3.077	.002	.009	3	1
UCEC	MIR4327 →	+0.305	+4.736	<.001	.003	3	1
UCEC	SNORA74C-1 →	+0.335	+2.671	.004	.005	3	1
UCEC	CLIC4P2 →	+0.148	+3.398	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

Exploration

FAM180B survival (RNA) · tumor vs normal (RNA) · all FAM180B data types